Showing posts with label initial research. Show all posts
Showing posts with label initial research. Show all posts

Thursday, September 24, 2009

RJA #6b: Search Strings

Search engine math-"+genetic+manipulation+(applications OR uses)+ (testing OR research)-"stem cells"-"+possible+uses+human+genetic+(manipulation OR engineering)+consequences+"genetic disease"-"stem cells"

Boolean-Possible OR potential uses OR applications AND genetic OR DNA AND manipulation OR engineering AND testing OR research OR exploring AND consequences OR outcomes-Potential OR possible NEAR use* OR application* AND genetic OR DNA NEAR manipulation OR engineering AND research AND consequences.

RJA #6a: Periodical Articles

--Google scholar
keywords: human, genetic, engineering, manipulation, genome
hits- 100,000
relevance- 3 out of 5

-Playing God? Human Genetic Engineering and the Rationalization of Public Bioethical Debate
Vol. 289 No. 10, March 12, 2003
by John H. Evans
page 304
http://jama.ama-assn.org/cgi/content/full/289/10/1313

-Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T2Y-418YGFH-3&_user=914312&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1022832183&_rerunOrigin=scholar.google&_acct=C000047910&_version=1&_urlVersion=0&_userid=914312&md5=eb1e7e2ff263f7d41031701cffced3e0
Copyright © 1999 Elsevier Science
by Larry L. Green

-Public Concerns in the United Kingdom about General and
Specific Applications of Genetic Engineering: Risk, Benefit,
and Ethics
Lynn J. Frewer, Chaya Howard and Richard Shepherd
Science Technology Human Values 1997; 22; 98
http://sth.sagepub.com/cgi/reprint/22/1/98

-Human gene therapy
WF Anderson
Science, Vol 256, Issue 5058, 808-813Copyright © 1992 by American Association for the Advancement of Science

-Gene Therapy Fulfilling Its Promise
Donald B. Kohn, M.D., and Fabio Candotti, M.D.
Volume 360:518-521 January 29, 2009 Number 5
http://content.nejm.org/cgi/content/full/360/5/518

-Human Genetic Enhancements: A Transhumanist Perspective
Journal
Springer Netherlands
Volume 37, Number 4 / December, 2003
Pages 493-506
Friday, August 11, 2006
http://www.springerlink.com/content/r45507622j852433/fulltext.pdf

--Directory of open access journals
keywords: genetic, engineering, human, genome, DNA
hits-21
relevance-3.5 out of 5

-Minichromosomes: The second generation genetic engineering tool
Aakash Goyal ; Pankaj Kumar Bhowmik, Lethbridge Research Center, Agriculture and Agri-Food Canada, Lethbridge, AB Canada T1J 4B1 ; Saikat Kumar Basu
2009 vol 2 issue 1 pg 1-8
http://www.doaj.org/doaj?func=abstract&id=340590&q1=human&f1=all&b1=and&q2=genetic%20engineering&f2=all&recNo=1

-Current ethical problems in cell biology
Josef Berger
Faculty of Social and Health Studies, University of South Bohemia, České Budějovice, Czech Republic
Received 10th July 2005.
Published online 2nd September 2005
Journal of applied biomedicine
volume 3, pg. 109–113
http://www.zsf.jcu.cz/jab/3_3/berger.pdf

writing ideas- human genetic engineering could cause the development of new, extremely effective new biological weapons

Sunday, September 6, 2009

RJA #3A

Genetic engineering @ wikipedia- direct manipulation unlike breeding, 5 step process, creation of living art forms (bioart), applications-mostly for vaccines thus far but promising for curing genetic disease. Has potential to alter human appearance, adaptability, intelligence, character, and behaviour. It can potentially be used in creating more dramatic changes.
biofact.com- Explains the difference between different types of genetic manipulation from natural selection (occurs naturally) to selective breeding, to cloning. This site has some interesting technical information about how some of these processes are done and also highlights some of the controversy on the subject.
eubios.info/Papers/HGT92- Has more information on public acceptance or lack thereof, and gives a semi-detailed description of why there's such an impassioned and fearful dislike of such technologies. Also, this site has statistical data on where human gene therapy and other applications of genetic manipulation are being used around the world.